CELLviewer, a lab-on-a-chip technology for and study of biological phenomena Purpose: Single-cell analysis is a fast growing field with a high impact in the research community owing to its numerous applications including cancer research, diagnostic, and drug discovery. In this context, microﬂuidics and lab-on-a-chip technology have emerged as the most promising avenue to address these […]
Celldynamics is online on Back to Work 24. We are ready for the equity CrowdFunding campaign. Follow the campaign on https://www.backtowork24.com/online-campaign.php?c=23-celldynamics
Luca Sereni and Daniele Gazzola present the CellDynamics Project to a group of investors belonging to the Back to Work and Sole 24 Ore network.
CELLviewer raccontato da Daniele Gazzola (presidente di CellDynamics) e da Simone Pasqua (Founder e Product Menager di CellDynamics) con l’ intervento del Dr. Parmegiani (IVF Laboratory Director presso GynePro Medical Centers).
Recent breakthroughs in 3-dimensional (3D) organoid cultures for many organ systems have led to new physiologically complex in vitro models to study human development and disease. Here, Dye BR and colleagues from Department of Cell and Developmental Biology (University of Michigan Medical School) expose the step-wise differentiation of human pluripotent stem cells (hPSCs) (embryonic and […]
Microgravity as a biological tool to examine host–pathogen interactions and to guide development of therapeutics
Space exploration programs have long been interested in the effects of spaceflight on biology. Bacterial behavior has been shown to be altered both in space and under simulated microgravity conditions. In some cases, bacteria appear attenuated, whereas in others virulence is enhanced. The microgravity environment can be exploited as a tool in the search for […]
Scaffold-free tissue formation in microgravity is a new method in regenerative medicine and an important topic in Space Medicine. As spaceflights are rare and extremely expensive, cell culture under simulated microgravity allows more comprehensive and frequent studies on the scaffold-free 3D tissue formation in some aspects, as a number of publications have proven during the […]
Liquid biopsy is a blood test involving the harvesting of tumor materials from peripheral blood. Tumor cells from non-blood body fluids have always been clinically available in cytological examinations but limited for use in differential diagnosis due to the low sensitivity of conventional cytopathology. With the recent significant progress in microfluidic and downstream molecular technologies, […]
Diverse subtypes of CTCs with cytogenetic abnormalities in hepatocellular carcinoma patients determine cancer relapse
Detection of hepatocellular carcinoma (HCC) circulating tumor cells (CTCs) performed with conventional strategies, is significantly limited due to inherently heterogeneous and dynamic expression of EpCAM, as well as degradation of cytokeratins during epithelial-to-mesenchymal transition, which inevitably lead to non-negligible false negative detection of such “uncapturable and invisible” CTCs. A novel SE-iFISH (SE, subtraction enrichment; iFISH, […]